Company profile

Shandong Xinchuang Biotechnology Co., LtdHe is mainly engaged in the research and development of biomedical technology, with bacterial oncolytic drugs, tumor cell therapy, stem cell and regenerative medicine, accurate diagnosis as the main research direction, focusing on innovative drugs, and using modern medical and pharmaceutical theory and high-tech to carry out multidisciplinary comprehensive research. With excellent R & D team, advanced scientific research equipment, fruitful R & D achievements, strict quality control system, standardized experimental facilities, perfect management mechanism, innovative cultural concept, sincere partners, and employee protection of rights and interests, it has strong strength and great influence in the field of biological new drug technology research and development, and is widely recognized by all walks of life.

1、Bacterial oncolytic drugs (biological class 1 new drug, approved by the national major new science and technology major special project, Project No. 2019zx09301166; now it has obtained the acceptance number of clinical trial cxsl2000177, and it is expected to obtain the approval of clinical trial from October to the end of the year)

2、Tumor cell therapy (NK, DC, car-t, CTL, etc., in clinical trials)

3、Stem cells and regenerative medicine (Research on the treatment of multiple diseases with autologous adipose derived mesenchymal stem cells and umbilical cord mesenchymal stem cells, and several batches of products have been prepared and frozen)

4、Accurate diagnosis (3 diagnostic kit products, under clinical verification, sorting out materials, preparing to apply for medical device registration certificate)

（1）Early rapid diagnosis kit for Alzheimer's disease (approved by Shandong major innovation project, subject No.: 2019jzzy011011)

（2）Padi2 and PADI4 multiple ELISA kits for early diagnosis of tumor (approved by Shandong major innovation project, subject No.: 2017cxgc1202)

（3）Diagnostic kit for minimal residual disease of leukemia

The company has 56 employees (40 full-time employees and 16 part-time employees), including 50 with bachelor's degree or above, 26 with master's degree and 10 with doctor's degree.

The company adopts the team building policy of combining introduction and training, introduces and trains academic leaders, adopts the guidance of mentoring, and actively builds expert teams: Hong Tao (academician of Chinese Academy of Engineering), Hou Yunde (academician of Chinese Academy of Engineering), Yu Jinming (academician of Chinese Academy of engineering, President of Shandong Cancer Hospital), Randy schekman (winner of Nobel Prize in physiology or medicine, United States) Academician of National Academy of Sciences), Ma Jing (former director of Shanghai safety assessment center, national drug evaluation expert), he Jinsheng (executive vice president, Professor, doctoral advisor, Institute of life science and Bioengineering, Beijing Jiaotong University, standing director of national Alzheimer's disease prevention and Treatment Association), Chang Xiaotian (scholar of Mount Tai and director of medical research center of Qianfoshan Hospital of Shandong Province) , Meng Hong (Professor of Shandong Medical College), Qin Hongmin (tenured professor of a & amp; M University of Texas, U.S.A., a distinguished expert funded by the Provincial Bureau of Foreign Affairs), Jiang Yandong (Professor of Harvard University), David Morgan (Professor of the University of South Florida), Cao Chuanhai (Professor of the University of South Florida), and Huang Jiaqiang (Professor of the National Cancer Institute of the United States).
Academician Hong Tao as the company introduced high-level talents (5150 innovative talents in Jinan City), and led the National 863 Project (Alzheimer's disease Alzheimer's disease) to the company for research and development, and the Provincial Department of human resources and social security awarded the academician workstation of the company.

One expert of "national talent project" was independently cultivated and three "national talent engineering experts" were introduced. Shandong Provincial Science and Technology Department awarded the "national talent project" expert workstation of the company.

The company now has instruments such as flow cytometry, anaerobic incubator, carbon dioxide incubator (15 units), biological safety cabinet (12 sets), full-automatic fluorescent inverted microscope, independent air supply isolation cage, multifunctional scanning imaging instrument, gel imaging analysis system, electrophoresis apparatus, refrigerating high speed centrifuge, multifunctional enzyme labelling instrument, fluorescent quantitative PCR instrument and other instruments. The total value of instruments and equipment is more than 20 million yuan.

In accordance with the requirements of national new drug research and development, the company has established a high standard cancer bacterial therapy Experimental Center (central laboratory, bacterial laboratory, cell laboratory); ）Cell and regenerative medicine experimental center (precision instrument room, purification room, central laboratory, etc.), animal feeding room, animal laboratory, pathology room, anatomy room, etc., as well as functional departments such as market development department, information development department, quality control department, financial secretary department, etc.

The company has established and completed the bacterial therapy technology management standards, cell immunotherapy technology management standards, laboratory safety management regulations, application data review management regulations, employee performance and attendance management methods, employee completion project commission method, employee significant contribution reward method, scientific research achievement promotion and transfer method, and employee technology There are 50 management methods for the company, such as salary management system.

With the help of external brain and external force, the company develops itself. At present, the company has established cooperation with famous universities at home and abroad (Harvard University, Griffith University of Australia, Shandong First Medical University, Beijing Jiaotong University, etc.) and scientific research institutions (Chinese Academy of engineering, Cancer Research Institute of National Institutes of Health (NCI), national Shanghai new drug safety evaluation center, etc.), well-known hospitals (General Hospital of Chinese people's Liberation Army (301 Hospital), Shandong Province More than 50 hospitals, including provincial cancer hospital, Shandong University Qilu Hospital, Tianjin Cancer Hospital, Henan Cancer Hospital, etc., have established good communication and cooperation relations.

It has undertaken 24 national, provincial and Jinan scientific research projects. Among them, class 1 new drug project won the national major new drug creation technology major special project (Project No.: 2019zx09301166), Shandong provincial key R & D plan (Project No.: 2017cxgc1407), China Innovation and Entrepreneurship Competition Award, which is one of the only two award-winning enterprises in biomedical field, and won the innovation competition action plan of small and medium-sized enterprises in Shandong Province First prize in the field of biomedicine; the project "development of lyophilized powder of Clostridium gloeosporioides spores, a new class of biological products for the treatment of nasopharyngeal carcinoma", won the first prize of technological innovation achievements of excellent staff in national energy chemical geological system; one employee won the labor medal of Shandong Province May 1st; two employees won the May 1st Labor Medal of Shandong Province and Jinan City; and 1 employee won the influence of economy One employee won the most beautiful science and technology worker in the high tech Zone.

The company has authorized 17 invention patents (5 in China, 7 in foreign countries and 4 in the world), and is applying for 8 invention patents (5 in China and 3 in foreign countries). Among them, the core patent of bacterial oncolytic project (ZL 201210310374.4) won the Chinese invention patent Excellence Award.

At present, the research projects of tumor diagnosis kit and early diagnosis kit for Alzheimer's disease have been approved by major innovation projects of Shandong Province (Project No.: 2017cxgc1202, 2019jzzy011011); stem cell and regenerative medicine project, tumor immunotherapy have made qualitative progress and breakthrough.

The research and development of each new drug project is a systematic project, which requires close cooperation and teamwork from all aspects in order to ensure the quality and complete the project quickly. Every employee is required to be a model, an example and a good colleague in cooperation. The company has a strict system of regular meeting and timely holding relevant special meetings when problems are found, so as to strengthen the coordination and cooperation of all aspects and accelerate the project progress.

Employees are the theme and master of the company, and the main force and fundamental driving force of the company's development. Therefore, respecting employees, caring for them, caring for them, and treating them as friends, relatives, and brothers and sisters are the highest principles in company management.

The company protects the rights and interests of employees and fulfills the commitment agreement to the letter. Ensure that wages are paid in full and on time, that the project commission is paid in full and on time, that five kinds of insurance are paid in time for employees, that the year-end bonus of the Spring Festival is withdrawn in full and in time, that the people who have made great contributions to the company are rewarded in time, and that the marriage and birth expenses are paid in time Education subsidies, ensure the timely distribution of lunch subsidies, guarantee the provision of collective dormitories for single employees, and ensure that employees are provided with good working and scientific research conditions and learning opportunities. At the same time, the company promises to help employees promote their professional and technical titles, settle down (the company's collective account), file storage, and other problems that need help or assistance. Employees are required to take the company as their own home, and ask the company for help whenever they have something to do. In this way, they can warm their hearts, condense their hearts and gather strength to do a good job.

The company is dedicated to meet the needs of its employees；

Employees are for the company -- do real work, and people are friends。